Targeting insulin-like growth factor axis in hepatocellular carcinoma
نویسندگان
چکیده
منابع مشابه
Targeting insulin-like growth factor axis in hepatocellular carcinoma
The insulin-like growth factor (IGF) axis contains ligands, receptors, substrates, and ligand binding proteins. The essential role of IGF axis in hepatocellular carcinoma (HCC) has been illustrated in HCC cell lines and in animal xenograft models. Preclinical evidence provides ample indication that all four components of IGF axis are crucial in the carcinogenic and metastatic potential of HCC. ...
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ژورنال
عنوان ژورنال: Journal of Hematology & Oncology
سال: 2011
ISSN: 1756-8722
DOI: 10.1186/1756-8722-4-30